Enabling technologies
The unit operations that comprise our Integrated Continuous Manufacturing lines are novel, and provide advantages over existing conventional batch technologies. They permit reactions and formulation steps that are not possible in batch.

Continuous Filtration
Our proprietary continuous, small scale rotary filtration and washing system purifies concentrated suspensions containing active pharmaceutical ingredients (APIs) or API intermediates.
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Continuous Drying
Our proprietary rapid, continuous, small-scale device forms dry powder from a concentrated or diluted suspension that contains active pharmaceutical ingredients (APIs).

Continuous Formulation
We have developed proprietary continuous technologies for the manufacturing of pharmaceutical drug products, which are able to be integrated with our upstream continuous processes, as well as the appropriate in-line PATs.
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Flow Chemistry
Our team has experience converting batch reactions to continuous ones, using a variety of reactors, which include plug flow reactors, continuously-stirred tank reactors (CSTRs), packed-bed reactors and trickle-bed reactors.

Crystallization
We have significant expertise converting batch crystallizations to continuous ones. Through the use of in-line PATs, we can determine the rates of nucleation and crystal-growth to create robust and reliable crystallizations systems.
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Polish Filtration
An automated continuous polish filtration system was developed at CONTINUUS to remove the suspended particulate matter from solutions. They system features two filters working in tandem for uninterrupted operation.
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PAT
At CONTINUUS, PAT tools are systematically deployed for various unit operations after demonstrating feasibility during the process characterization activities with the aim to implement and ensure the quality and safety of our products

Solvent Recovery
A continuous Solvent Recovery system for was designed for our end-to-end ICM Line. The recovered purified solvents can then be reused in the manufacturing process, reducing overall solvent use and waste.

Control Systems
Integrated control systems are paramount for ICM lines, as they allow for real-time responses to process disturbances. They enable operators to visualize the entire process and respond accordingly.